I have a Titleist Staff Bag! I use a produc(s) called Lexol. Both Cleaner (orange bottle) and Conditioner (brown bottle). I clean my baby after every single round/practice session! This stuff is amazing! I also use a little lube to use on the zippers, etc.., just to prevent them from getting stuck, etc.. If you can find Lexol products, perhaps some Meguiar's leather wipes would do the trick?!

I just picked up a midsize staff bag.  The new Titleist staff bags look great.   Good info on the Lexol.  I'll check that out.